| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a morbidity model animal for itchiness accompanying the depression of renal functions caused by kidney diseases, not existing conventionally, that is, the morbidity model animal for evaluating the itchiness by using an ICGN type mouse, a method of treating, a treating agent and a method of prevention or a method for evaluating a preventing agent, by using the animal. Ž<P>SOLUTION: This ICGN type mouse for evaluating the itchiness associated with the depression of the renal functions, characterized by having depressed renal functions and showing itchiness-associated behavior is found out, and further, the animal is found out to be useful for the method for treating the itchiness accompanying the depression of renal functions caused by the kidney diseases, treating agent, method of prevention or method for evaluating the preventing agent. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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