发明名称 |
PAPILLOMAVIRUS VACCINES |
摘要 |
A nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a therapeutic composition thereof is formulated into a drug product useful for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus; particular such vectors are nucleic acid molecules containing a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3′ portion of the first nucleotide which in the natural content is 100% identical to the 5′ portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%.
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申请公布号 |
US2010143408(A1) |
申请公布日期 |
2010.06.10 |
申请号 |
US20080449197 |
申请日期 |
2008.01.29 |
申请人 |
BAUDIN MARTINE;BALLOUL JEAN-MARC;SILVESTRE NATHALIE |
发明人 |
BAUDIN MARTINE;BALLOUL JEAN-MARC;SILVESTRE NATHALIE |
分类号 |
A61K39/12;A61P31/12;C12N15/63 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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地址 |
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