| 发明名称 |
METHOD OF BLOCKING SIGNAL PATH ACTIVATED BY TGF-beta FACTOR OF VgI IN ANIMAL CELLS |
| 摘要 |
FIELD: chemistry; biochemistry. ^ SUBSTANCE: invention relates to molecular biology, specifically to proteins which regulate cell differentiation through inhibition of the TGF-beta cell superfamily. The invention is aimed at treating and preventing diseases related to human VgI orthologs. Noggin2 protein which contains VgI protein is injected into tissue in amount which is efficient for inhibiting VgI activity. ^ EFFECT: invention enables to solve the task of blocking the signal path activated by the TGF-beta factor of VgI in aniamal cells. ^ 2 dwg, 4 ex |
| 申请公布号 |
RU2391352(C1) |
申请公布日期 |
2010.06.10 |
| 申请号 |
RU20080142089 |
申请日期 |
2008.10.24 |
| 申请人 |
UCHREZHDENIE ROSSIJSKOJ AKADEMII NAUK INSTITUT BIOORGANICHESKOJ KHIMII IM. AKADEMIKOV M.M. SHEMJAKINA I JU.A. OVCHINNIKOVA RAN;ROSSIJSKAJA FEDERATSIJA, OT IMENI KOTOROJ VYSTUPAET FEDERAL'NOE AGENTSTVO PO NAUKE I INNOVATSIJAM |
发明人 |
BAJRAMOV ANDREJ VJACHESLAVOVICH;EROSHKIN FEDOR MIKHAJLOVICH;MARTYNOVA NATAL'JA JUR'EVNA;ERMAKOVA GALINA VLADIMIROVNA;SEREBRJAKOVA MARINA VALENTINOVNA;SOLOV'EVA ELENA ANATOL'EVNA;ZARAJSKIJ ANDREJ GEORGIEVICH |
| 分类号 |
C07K14/475;G01N33/68 |
主分类号 |
C07K14/475 |
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