| 发明名称 |
RAF INHIBITORS AND THEIR USES |
| 摘要 |
The present invention provides imidazooxazole and imidazothiazole compounds and their syntheses. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF V600E. The compounds are useful for the treatment of cell proliferative disorders such as cancer.
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| 申请公布号 |
CA2744713(A1) |
申请公布日期 |
2010.06.10 |
| 申请号 |
CA20092744713 |
申请日期 |
2009.12.04 |
| 申请人 |
ARQULE, INC. |
发明人 |
LAPIERRE, JEAN-MARC;LIU, YANBIN;TANDON, MANISH;ASHWELL, MARK A. |
| 分类号 |
C07D498/04;A61K31/424;A61K31/429;A61P35/00;C07D513/04 |
主分类号 |
C07D498/04 |
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