| 摘要 |
A transdermal therapeutic system embodied as a matrix or reservoir system is characterized by - a content of at least one basic- or neutral-reacting pharmaceutical active agent - a content of a pressure-sensitive adhesive polymer which possesses as part of its chain acrylic acid or methacrylic acid units, the content of the carboxyl groups, relative to the mean polymer mass, being 0.5 to 10.0% (w/w) and the carboxyl groups being present stoichiometrically at 5 to 100%, preferably 10 to 50%, in form of alkali salts or alkaline earth salts. Water-binding additives may also be present, for reducing the sensitivity to moisture.
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