发明名称 TYROSINE KINASE INHIBITOR COMPOUND, ISOMER THEREOF OR PHARMACEUTICALLY ALLOWABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
摘要 The present invention relates to a compound expressed in the following chemical formula 1, to an isomer thereof, or to a pharmaceutically allowable salt thereof. The compound expressed in chemical formula 1 inhibits the tyrosine kinase activity of Discoidin Domain Receptor 1 (DDR1) and Discoidin Domain Receptor 2 (DDR2), and thus can be valuably used in the prevention or treatment of diseases such as a cancer, hepatocirrhosis, arteriosclerosis, rheumatoid arthritis, osteoarthritis, and the like, which are known to be mainly caused by an excessive activation of Discoidin Domain Receptor 1 or Discoidin Domain Receptor 2.
申请公布号 WO2010062038(A2) 申请公布日期 2010.06.03
申请号 WO2009KR06050 申请日期 2009.10.20
申请人 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;LEGOCHEM BIOSCHENCES LTD.;YANG, BEOM-SEOK;KIM, SUN YOUNG;CHO, JONG UN;LEE, HYANG SOOK;WOO, SUNG HO;PARK, TAE KYO;KIM, YONG ZU;KIM, SEUNG TAE;LEE, HONG BUM 发明人 YANG, BEOM-SEOK;KIM, SUN YOUNG;CHO, JONG UN;LEE, HYANG SOOK;WOO, SUNG HO;PARK, TAE KYO;KIM, YONG ZU;KIM, SEUNG TAE;LEE, HONG BUM
分类号 C07D513/04 主分类号 C07D513/04
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