摘要 |
The present invention relates to a compound expressed in the following chemical formula 1, to an isomer thereof, or to a pharmaceutically allowable salt thereof. The compound expressed in chemical formula 1 inhibits the tyrosine kinase activity of Discoidin Domain Receptor 1 (DDR1) and Discoidin Domain Receptor 2 (DDR2), and thus can be valuably used in the prevention or treatment of diseases such as a cancer, hepatocirrhosis, arteriosclerosis, rheumatoid arthritis, osteoarthritis, and the like, which are known to be mainly caused by an excessive activation of Discoidin Domain Receptor 1 or Discoidin Domain Receptor 2. |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;LEGOCHEM BIOSCHENCES LTD.;YANG, BEOM-SEOK;KIM, SUN YOUNG;CHO, JONG UN;LEE, HYANG SOOK;WOO, SUNG HO;PARK, TAE KYO;KIM, YONG ZU;KIM, SEUNG TAE;LEE, HONG BUM |
发明人 |
YANG, BEOM-SEOK;KIM, SUN YOUNG;CHO, JONG UN;LEE, HYANG SOOK;WOO, SUNG HO;PARK, TAE KYO;KIM, YONG ZU;KIM, SEUNG TAE;LEE, HONG BUM |