| 发明名称 |
Substituted benz-azoles and methods of their use as inhibitors of Raf kinase |
| 摘要 |
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
|
| 申请公布号 |
US7728010(B2) |
申请公布日期 |
2010.06.01 |
| 申请号 |
US20050282939 |
申请日期 |
2005.11.18 |
| 申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS, INC. |
发明人 |
AMIRI PAYMAN;FANTL WENDY;HANSEN TERESA;LEVINE BARRY HASKELL;MCBRIDE CHRISTOPHER;POON DANIEL J;RAMURTHY SAVITHRI;RENHOWE PAUL A;SHAFER CYNTHIA M;SUBRAMANIAN SHARADHA;SUNG LEONARD |
| 分类号 |
A61K31/423;A61K31/4439;A61K31/444;A61K31/4545;A61K31/46;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/55;A61K31/551;A61K45/00;A61P35/00;A61P43/00;C07D263/58;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/14;C07D413/04;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D451/14;C07D453/02 |
主分类号 |
A61K31/423 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
