摘要 |
A process for synthesis of 2,4-dichloro-5-fluoro acetophenone (DCFA) is disclosed. The process comprises first reacting 3,4-dichloronitrobenzene with potassium fluoride having bulk density in the range of 0.2 to 1.3, to form a fluorinated intermediate product, then reacting the intermediate product with chlorine to form dichlorofluorobenzene and finally acylating dichlorofluorobenzene using an acylating agent to form a mixture containing DCFA along with impurities, followed by purification and enrichment of DCFA in the mixture by melt crystallization. |
申请人 |
ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD.;MANDAL, SISIR;PATIL, NARENDRA;SULEMAN, INAMDUR;MORE, VINOD;PURI, PRASHANT |
发明人 |
MANDAL, SISIR;PATIL, NARENDRA;SULEMAN, INAMDUR;MORE, VINOD;PURI, PRASHANT |