发明名称 |
METHODS FOR DETECTING IgH/BCL-1 CHROMOSOMAL TRANSLOCATION |
摘要 |
<p>The invention provides methods for detection of Bcl-1 nucleic acid in acellular body fluid. The methods can be used to detect the IgH/Bcl-1 translocations (11;14)(q13;q32) in acellular body fluid. The chromosomal translocation (11;14)(q13;q32) is often associated with mantle cell (centrocytic) lymphoma and occasionally in other B-cell neoplasms, notably myeloma. The invention is useful in the diagnosis of mantle cell lymphoma (MCL) and also for determining the prognosis of the disease.</p> |
申请公布号 |
WO2010059499(A1) |
申请公布日期 |
2010.05.27 |
申请号 |
WO2009US64158 |
申请日期 |
2009.11.12 |
申请人 |
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED;ALBITAR, MAHER |
发明人 |
ALBITAR, MAHER |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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