| 发明名称 |
Homoharringonine alone or combined with other agents for use in treating chronic myelogenous leukemia resistant or intolerant to sti571 |
| 摘要 |
<p>The present invention concerns a method of treating chronic myelogenous leukemia, a related myeloproliferative disorder or a Ph-positive acute lymphocytic leukemia in a subject animal, comprising:
(a) selecting or identifying an animal suffering from chronic myelogenous leukemia or a related myeloproliferative disorder and showing resistance or intolerance to treatment with STI571; and
(b) administering to the animal homoharringtonine.</p><p>In a preferred embodiment, the animal is a human being.</p> |
| 申请公布号 |
EP2177223(A3) |
申请公布日期 |
2010.05.19 |
| 申请号 |
EP20090172828 |
申请日期 |
2002.09.05 |
| 申请人 |
CHEMGENEX PHARMACEUTICALS LIMITED |
发明人 |
BLANCHARD, JULIE;MAHON, FRANCOIS-XAVIER;MALOISEL, FREDERICK;ROBIN, JEAN-PIERRE;MAISSONNEUVE, HERVE |
| 分类号 |
A61K31/55;C07D491/14;A61K31/496;A61K31/506;A61K31/7052;A61K31/7068;A61K38/21;A61K45/00;A61P35/02 |
主分类号 |
A61K31/55 |
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