| 发明名称 |
NEW CRYSTALLINE SALT FORMS OF A 5,6,7,8-TETRAHYDRO-1,2,4- TRIAZOLO[4,3-A]PYRAZINE DERIVATIVE |
| 摘要 |
<p>This invention provides novel crystalline acid salt forms of 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine, i.e. sitagliptin, to processes for their preparation and isolation, and to pharmaceutical compositions comprising the same.</p> |
| 申请公布号 |
WO2010012781(A3) |
申请公布日期 |
2010.05.14 |
| 申请号 |
WO2009EP59821 |
申请日期 |
2009.07.29 |
| 申请人 |
MEDICHEM, S.A.;WINTER, STEPHEN BENEDICT DAVID;BENITO VELEZ, MONICA;DURAN LOPEZ, ERNEST |
发明人 |
WINTER, STEPHEN BENEDICT DAVID;BENITO VELEZ, MONICA;DURAN LOPEZ, ERNEST |
| 分类号 |
C07D487/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
