摘要 |
Hard shell capsules filled with a normally hygroscopic formulation and a method for producing the same is described. The hard shell capsules are filled with a normally hygroscopic formulation including, for example, an excipient, and optionally an active compound. The water content of the formulation and the hard shell capsule are in equilibration, and the formulation is hydrated by an amount selected to control equilibrium between said formulation and the hard shell capsule, and to provide a structurally stable hard shell capsule. The active compound may be a protein or peptide.
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