发明名称 Alkyl-substituted tetrahydropyranes as aromatic materials
摘要 Alkylated tetrahydropyran compounds (I) are new, where (I) excludes 2,6-dimethyl-3-(1-methylethenyl)-tetrahydropyran, 6-methyl-3-(1-methylethenyl)-2-(2-methylpropyl)-tetrahydropyran, 2-methyl-3-n-propyl-tetrahydropyran or 2-methyl-3-n-butyl-tetrahydropyran. Alkylated tetrahydropyran compounds of formula (I) are new, where (I) excludes 2,6-dimethyl-3-(1-methylethenyl)-tetrahydropyran, 6-methyl-3-(1-methylethenyl)-2-(2-methylpropyl)-tetrahydropyran, 2-methyl-3-n-propyl-tetrahydropyran or 2-methyl-3-n-butyl-tetrahydropyran. R 1 : H, 1-3C alkyl group or 2-3C alkenyl group; R 2 : 3-4C alkyl or alkenyl group; and R 3 : 1-5C alkyl group. Independent claims are included for: (1) a mixture comprising (a) one, two, three, four or more of the above alkylated tetrahydropyran, (b) one or more (volatile) aroma- and/or flavors, preferably one or more substance(s) consisting of substances with physiological cooling effect, flavors without physiological cooling effect, trigeminal or mouthwash effective substances without physiological cooling effect or flavor modulating substances, and (c) optionally a carrier; and (2) the preparation of (I). [Image] ACTIVITY : Antitussive; Virucide; Antiinflammatory; Analgesic; Insect Repellent. MECHANISM OF ACTION : None given.
申请公布号 EP2168957(A2) 申请公布日期 2010.03.31
申请号 EP20090176696 申请日期 2009.11.20
申请人 SYMRISE GMBH & CO. KG 发明人 OERTLING, HEIKO;BROCKE, CONSTANZE;LOGES, HUBERT;MACHINEK, ARNOLD
分类号 C07D309/04;A23G3/36;A23G4/06;A23L2/39;A23L27/00;A61K8/49;A61K31/351;A61P43/00;A61Q11/00 主分类号 C07D309/04
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