发明名称 STABLE NON-AQUEOUS PHARMACEUTICAL COMPOSITIONS
摘要 The present invention relates to shelf stable non-aqueous pharmaceutical compositions, and to the use thereof in methods of treating diabetes and hyperglycaemia. The composition comprises a dehydrated therapeutically active insulinotropic peptide, and at least one semi-polar protic organic solvent which insulinotropic peptide has been dehydrated at target pH which is at least 1pH unit from the pI of the peptide in aqueous solution.
申请公布号 EP2164458(A1) 申请公布日期 2010.03.24
申请号 EP20080760278 申请日期 2008.05.30
申请人 NOVO NORDISK A/S 发明人 BJERREGAARD JENSEN, SIMON;HAVELUND, SVEND;FOEGER, FLORIAN ANDERS
分类号 A61K9/00;A61K9/08;A61K9/12;A61K9/16;A61K9/28;A61K47/10 主分类号 A61K9/00
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