发明名称 |
STABLE NON-AQUEOUS PHARMACEUTICAL COMPOSITIONS |
摘要 |
The present invention relates to shelf stable non-aqueous pharmaceutical compositions, and to the use thereof in methods of treating diabetes and hyperglycaemia. The composition comprises a dehydrated therapeutically active insulinotropic peptide, and at least one semi-polar protic organic solvent which insulinotropic peptide has been dehydrated at target pH which is at least 1pH unit from the pI of the peptide in aqueous solution. |
申请公布号 |
EP2164458(A1) |
申请公布日期 |
2010.03.24 |
申请号 |
EP20080760278 |
申请日期 |
2008.05.30 |
申请人 |
NOVO NORDISK A/S |
发明人 |
BJERREGAARD JENSEN, SIMON;HAVELUND, SVEND;FOEGER, FLORIAN ANDERS |
分类号 |
A61K9/00;A61K9/08;A61K9/12;A61K9/16;A61K9/28;A61K47/10 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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