发明名称 |
Alzheimer's disease diagnosis based on mitogen-activated protein kinase phosphorylation |
摘要 |
A method of diagnosing Alzheimer's disease in a patient comprises determining whether the phosphorylation level of an indicator protein in cells of the patient after stimulus with an activator compound is abnormally elevated as compared to a basal phosphorylation level, the indicator protein being e.g. Erk1/2 and the activator compound being e.g. bradykinin.
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申请公布号 |
US7682807(B2) |
申请公布日期 |
2010.03.23 |
申请号 |
US20040469164 |
申请日期 |
2004.07.19 |
申请人 |
BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE |
发明人 |
ZHAO WEI-QIN;ALKON DANIEL L. |
分类号 |
G01N33/50;G01N33/567;A61K45/00;A61P25/28;A61P43/00;C12N5/10;C12Q1/00;C12Q1/02;C12Q1/48;G01N33/00;G01N33/15;G01N33/53;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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