METHODS OF TREATING COGNITIVE DISORDERS BY INHIBITION OF GPR12
摘要
<p>The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or Gpr12 function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating Gpr12-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation by inhibiting Gpr12 function and methods for treating a defect in performance of a hippocampal-dependent cognitive task by inhibiting Gpr12 function.</p>
申请公布号
WO2008144453(A9)
申请公布日期
2010.03.18
申请号
WO2008US63804
申请日期
2008.05.15
申请人
HELICON THERAPEUTICS, INC.;PETERS, MARCO;SCOTT, RODERICK E.M.;TULLY, TIMOTHY P.
发明人
PETERS, MARCO;SCOTT, RODERICK E.M.;TULLY, TIMOTHY P.