发明名称 |
IMMUNOGLOBULIN CLEAVAGE FRAGMENTS AS DISEASE INDICATORS AND COMPOSITIONS FOR DETECTING AND BINDING SUCH. |
摘要 |
<p>The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions.</p> |
申请公布号 |
MX2010001616(A) |
申请公布日期 |
2010.03.15 |
申请号 |
MX20100001616 |
申请日期 |
2008.08.04 |
申请人 |
CENTOCOR ORTHO BIOTECH INC. |
发明人 |
JORDAN, ROBERT;PETRONE, DIANE D.;RYAN, MARY |
分类号 |
C07K14/435;C07K16/18 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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