| 摘要 |
The invention provides direct processes and related catalysts for the syntheses of trisubstituted chiral pyrrolidines, piperidines, tetrahydrothiophenes, and thianes by highly enantio- and diastereoselective cascade Michael-Michael reaction of a, ß-unsaturatedaldehydes with /ra/25-?-protected amino a, ß-unsaturated esters. |
