| 摘要 |
PROBLEM TO BE SOLVED: To provide an Actinomyces strain which can produce a Rosamicin derivative in which Mycinose is added at C-23 position of a lactone ring of a Rosamicin-like 16-membered macrolide, and a method for producing Rosamicin derivatives using the same. SOLUTION: The Actinomyces strain is obtained by introducing Mycinose biosynthesis gene into an Actinomyces strain which can produce Rosamicin-like 16-membered macrolide, and can produce a Rosamicin derivative in which Mycinose is added at C-23 position of a lactone ring of a Rosamicin. COPYRIGHT: (C)2010,JPO&INPIT |
