摘要 |
<p>The present invention provides a composition for transdermal or transmucosal administration, which is useful as an anti-Alzheimer's drug, an antiparkinson drug, an antidepressant, a psychoactive drug, or a therapeutic agent for drug dependence. The composition for transdermal or transmucosal administration comprising an effective dose of a racemate or an optically acceptable substance of 1-(benzofuran-2-yl)-2-propylaminopentane or a pharmacologically acceptable salt thereof and a vehicle, which can be administered without an invasion of skin and mucous membrane, is an excellent agent serving as an anti-Alzheimer's drug, an antiparkinson drug, an antidepressant, a psychoactive drug or a therapeutic agent for drug dependence, which can allow its active ingredient in a sufficient effective amount to stably arrive, through the skin and mucous membrane, at a body or a brain and is free of disadvantages such as a reduction in an active component caused by a first pass effect in a liver, as well as pains, damages or infections.</p> |
申请人 |
FUJIMOTO CO., LTD. |
发明人 |
YONEDA, FUMIO;OHDE, HIRONORI;WATANABE, MAYUMI;SUGIMOTO, MIKIYO;KAMADA, TAKAHIRO;HUKUMOTO, MIZUE;TAKASE, AZUSA;HOSHINO, NAOYA |