发明名称 Adhesive preparation
摘要 An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.
申请公布号 US2010047328(A1) 申请公布日期 2010.02.25
申请号 US20090588721 申请日期 2009.10.26
申请人 HISAMITSU PHARMACEUTICAL CO., INC. 发明人 TSURUDA KIYOMI;YAMASOTO SHINJI;SHOHO KOUKI;NAKANISHI MASARU
分类号 A61K9/70;A61K31/60;A61P17/02 主分类号 A61K9/70
代理机构 代理人
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