| 摘要 |
<P>PROBLEM TO BE SOLVED: To modulate effect of GDF-8 on a cell. <P>SOLUTION: Provided is a use of a protein, GASP1, comprising at least one follistatin domain to modulate the level or activity of growth and differentiation factor-8 (GDF-8). More particularly, it relates to the use of GASP1 for treating disorders that are related to modulation of the level or activity of GDF-8. It is useful for treating muscular disorders and diseases, particularly those in which an increase in muscle tissue is therapeutically beneficial. It is also useful for treating diseases and disorders related to metabolism, adipose tissue, and bone degeneration. <P>COPYRIGHT: (C)2010,JPO&INPIT |
