发明名称 MACROMOLECULAR DIFFUSION AND RELEASE FROM SELF-ASSEMBLED BETA-HAIRPIN PEPTIDE HYDROGELS
摘要 A hydrogel for delayed release of an anionic macromolecule, wherein the hydrogel comprises the anionic macromolecule, 150 mM NaCl, and a peptide selected from the group consisting of SEQ ID NO:1 through SEQ ID NO:33 in an aqueous medium at a pH of 7.4; wherein the anionic macromolecule has an isoelectric point of at most 6.8; and wherein the hydrogel is capable of retaining at least 25% of the anionic macromolecule after 28-day extraction at 37° C. with a pH=7.4 BTP buffer containing 150 mM NaCl.
申请公布号 US2010034881(A1) 申请公布日期 2010.02.11
申请号 US20090533708 申请日期 2009.07.31
申请人 THE UNIVERSITY OF DELAWARE 发明人 SCHNEIDER JOEL P.;BRANCO MONICA C.;POCHAN DARRIN J.;WAGNER NORMAN J.
分类号 A61K9/107 主分类号 A61K9/107
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