摘要 |
The invention relates to marker reagents of respective formulae (C) or (D), where R1 is in particular a detectable marker, R2, R3 are, independently, H, NO2 Cl, Br, F, I, OR, SR, NR2, NHCOR, COOR where R = alkyl or aryl, R4 is H,alkyl or aryl, L is a bridging arm. The invention further relates to a method for synthesising a marker reagent, a method for marking a biological molecule, a marked biological molecule obtained by said method, a method for marking and fragmenting a single or double strand nucleic acid, a marked nucleic acid obtained by said method, a detection kit for a target nucleic acid comprising a marked nucleic acid, a solid support to which a reagent is fixed and a method for trapping nucleic acids. The invention is preferably applied to diagnostics. |
申请人 |
BIOMERIEUX;UNIVERSITE DE STRASBOURG;CNRS;LAURENT, ALAIN;LAAYOUN, ALI;KOTERA, MITSUHARA |
发明人 |
LAURENT, ALAIN;LAAYOUN, ALI;KOTERA, MITSUHARA |