发明名称 |
Compositions Comprising MG29 Nucleic Acids, Polypeptides, and Associated Methods of Use |
摘要 |
Disclosed herein are compositions and methods for treatment of muscle dysfunction (including sarcopenia) and other diseases involving skeletal muscle, including age-related muscle dysfunction. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal muscle disorder, including those related to thr normal aging process. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ regulation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced.
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申请公布号 |
US2010017901(A1) |
申请公布日期 |
2010.01.21 |
申请号 |
US20090504331 |
申请日期 |
2009.07.16 |
申请人 |
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY |
发明人 |
MA JIANJIE;WEISLEDER NOAH |
分类号 |
A01K67/00;A61K31/7088;A61K38/00;C07H21/04;C12Q1/68 |
主分类号 |
A01K67/00 |
代理机构 |
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代理人 |
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地址 |
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