发明名称 INDOLEDIONE DERIVATIVE
摘要 <p>A compound represented by the general formula (I-a): [wherein R 1a and R 2a each means hydrogen, lower cycloalkyl, lower alkyl, etc.; R 3a means hydrogen, lower cycloalkyl, lower alkyl, etc.; R 4a and R 5a each means lower alkyl, lower cycloalkyl, etc. or R 4a and R 5a are bonded to each other to form lower cycloalkylidene; and R 6a means lower alkyl, lower haloalkyl, etc.]. This compound functions as an LCE inhibitor and is useful as a therapeutic agent for various circulatory diseases, nervous diseases, metabolic diseases, reproductive diseases, digestive tract diseases, neoplasm, infectious diseases, etc.</p>
申请公布号 EP2145884(A1) 申请公布日期 2010.01.20
申请号 EP20080738975 申请日期 2008.03.27
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 TAKAHASHI, TOSHIYUKI;NAGASE, TSUYOSHI;SATO, NAGAAKI
分类号 C07D401/14;A61K31/4155;A61K31/4439;A61P1/00;A61P1/04;A61P1/16;A61P1/18;A61P3/04;A61P3/06;A61P3/10;A61P3/12;A61P5/00;A61P5/50;A61P9/04;A61P9/10;A61P9/12;A61P11/16;A61P13/12;A61P15/00;A61P15/08 主分类号 C07D401/14
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