CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF
摘要
The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
申请公布号
WO2008083312(A3)
申请公布日期
2010.01.14
申请号
WO2007US89100
申请日期
2007.12.28
申请人
MEDAREX, INC.;SUFI, BILAL;GUERLAVAIS, VINCENT;CHEN, LIANG;GANGWAR, SANJEEV;ZHANG, QIAN;PASSMORE, DAVID, B.
发明人
SUFI, BILAL;GUERLAVAIS, VINCENT;CHEN, LIANG;GANGWAR, SANJEEV;ZHANG, QIAN;PASSMORE, DAVID, B.
