| 发明名称 |
AGONIST ANTI-TRK-C MONOCLONAL ANTIBODIES |
| 摘要 |
The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention andior treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy. |
| 申请公布号 |
US2010003261(A1) |
申请公布日期 |
2010.01.07 |
| 申请号 |
US20090478501 |
申请日期 |
2009.06.04 |
| 申请人 |
|
发明人 |
DEVAUX BRIGITTE;HONGO JO-ANNE;PRESTA LEONARD G.;SHELTON DAVID L. |
| 分类号 |
A61K39/395;C12N15/09;A61K48/00;A61P9/00;A61P25/00;A61P25/02;A61P25/28;C07K16/00;C07K16/28;C07K16/32;C12N5/10;C12N15/02;C12N15/13;C12P21/08 |
主分类号 |
A61K39/395 |
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