CD9-SPECIFIC HUMAN ANTIBODY

摘要

PURPOSE: A CD9-specific human antibody is provided to suppress cancer cell line and prevent and treat CD9 overexpressed cancer. CONSTITUTION: A CD9-specific human antibody contains a heavy chain having variable region with HCDR and light chain having variable region with LCDR. A method for preparing the CD9-specific human antibody comprises: a step of preparing an expression vector having a gene encoding a polypeptide corresponding to a fragment having immunological activation of light chain and heavy chain; a step of introducing the expression vector to a host cell to prepare a transformant; a step of culturing the transformant; and a step of isolating antibodies from the culture medium. A pharmaceutical composition for preventing and treating gastric cancer or ovarian cancer contains the CD9-specific human antibody.