PROCESS FOR PREPARING SUBSTITUTED BENZOTHIAZINOINDOLES

摘要

A process for the preparation of substituted benzothiazinoindoles of general formula (I)wherein R, R, and Rare independently selected from hydrogen, chloro, fluoro, amino, nitro, cyano, CHO, (C-C)alkyl, perhalo(C-C)alkyl, (C-C)alkoxy, aryl, aralkyl, aralkoxy, (C5-C7)heterocyclyl, (C-C)heterocyclylalkyl, (C-C)heterocyclyloxy, acyl, acetyl, alkylamino, aminoalkyl, amide, hydroxyalkyl, carboxylic acid and its derivatives, while Ris selected hydrogen, (C-C)alkyl, aryl and carboxylic acid and its derivatives is disclosed, said process comprising cyclization of compound of general formula-II, (i.e. substituted 1-benzenesulfonyl-7-bromo-lH-indole), formula (II)wherein R, R, and Rusing suitable catalyst and solvents wherein.