发明名称 Quinoxalinyl tripeptide hepatitis C virus inhibitors
摘要 The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 US7635683(B2) 申请公布日期 2009.12.22
申请号 US20060499917 申请日期 2006.08.04
申请人 ENANTA PHARMACEUTICALS, INC. 发明人 GAI YONGHUA;NIU DEQIANG;OR YAT SUN;WANG ZHE
分类号 A61K38/06 主分类号 A61K38/06
代理机构 代理人
主权项
地址