发明名称 BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
摘要 The present invention is directed to compounds of formula I: (see formula I) which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularl y type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions i n the prevention or treatment of such diseases in which the dipeptidyl peptida se- IV enzyme is involved.
申请公布号 CA2502269(C) 申请公布日期 2009.12.22
申请号 CA20032502269 申请日期 2003.10.14
申请人 MERCK & CO., INC. 发明人 LIANG, GUI-BAI;BIFTU, TESFAYE;QIAN, XIAOXIA;WEBER, ANN E.;FENG, DANQING DENNIS
分类号 C07D243/08;A61K;A61K31/55;A61K31/551;A61P3/10;C07D307/94;C07D401/06;C07D403/06;C07D405/12;C07D405/14;C07D491/107;C07K5/06 主分类号 C07D243/08
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