发明名称 |
BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES |
摘要 |
The present invention is directed to compounds of formula I: (see formula I) which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularl y type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions i n the prevention or treatment of such diseases in which the dipeptidyl peptida se- IV enzyme is involved.
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申请公布号 |
CA2502269(C) |
申请公布日期 |
2009.12.22 |
申请号 |
CA20032502269 |
申请日期 |
2003.10.14 |
申请人 |
MERCK & CO., INC. |
发明人 |
LIANG, GUI-BAI;BIFTU, TESFAYE;QIAN, XIAOXIA;WEBER, ANN E.;FENG, DANQING DENNIS |
分类号 |
C07D243/08;A61K;A61K31/55;A61K31/551;A61P3/10;C07D307/94;C07D401/06;C07D403/06;C07D405/12;C07D405/14;C07D491/107;C07K5/06 |
主分类号 |
C07D243/08 |
代理机构 |
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