发明名称 |
SPHINGOSINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND SPHINGOMYELINASE INHIBITOR |
摘要 |
An object of the invention is to provide a novel sphingosine compound with an inhibitory activity against sphingomyelinase, and a method for producing the sphingosine compound.
The novel sphingosine compound or a salt thereof according to the invention is represented by Formula (1):
wherein one of R 1 and R 2 is hydrogen, and the other is a group represented by Formula (G):
wherein n is 0 or 1; and R 3 is hydrogen, C 1-23 alkyl, C 3-8 cycloalkyl, C 2-6 alkenyl, C 1-6 alkoxy, C 3-8 cycloalkyloxy, phenyl, or furil.
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申请公布号 |
EP2133335(A1) |
申请公布日期 |
2009.12.16 |
申请号 |
EP20080721356 |
申请日期 |
2008.03.05 |
申请人 |
OTSUKA CHEMICAL CO., LTD. |
发明人 |
NISHIZAWA, MUGIO;IMAGAWA, HIROSHI;SAKURAI, JUN;ODA, MASATAKA |
分类号 |
A61P3/10;C07D213/22;A61K31/44;A61P3/04;A61P9/00;A61P9/10;A61P13/12;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P37/02;A61P43/00 |
主分类号 |
A61P3/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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