| 发明名称 |
Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa |
| 摘要 |
<p>The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoaguability or fibrotic changes.</p> |
| 申请公布号 |
AU2009254257(A1) |
申请公布日期 |
2009.12.10 |
| 申请号 |
AU20090254257 |
申请日期 |
2009.05.22 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
MARK BROENSTRUP;ANJA GLOBISCH;HERMAN SCHREUDER;CHRISTOPHER KALLUS;MICHAEL WAGNER;ANDREAS EVERS |
| 分类号 |
C07D413/14;A61K31/553;A61P7/00;C07D273/01 |
主分类号 |
C07D413/14 |
| 代理机构 |
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| 主权项 |
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| 地址 |
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