摘要 |
The invention relates to processes for preparing 17-alkynyl-7-hydroxy- steroids, such as 17-Ethynyl-10R13S-dimethyl 2,3,4,7,8R,9S, 10,11,12,13,14S,15,16,17-hexadecahydro-1 H-cyclopenta[a]phenanthrene- 3R,7R,17S-triol (also referred to as 17a-ethynyl-androst-5-ene-3ß,7ß,17ß-triol), that are essentially free of process impurities having binding activity at nuclear estrogen receptors. |
申请人 |
HOLLIS-EDEN PHARMACEUTICALS, INC.;WHITE, STEVEN, K.;GE, YU;HUANG, YUJIN |
发明人 |
WHITE, STEVEN, K.;GE, YU;HUANG, YUJIN |