摘要 |
<p>A compound of the formula CH3(CH2)n-RA-(CH2)m-(CH=CH)q-(CH2)p-X wherein RA = (a); q = 0or 1; m and p are independently selected integers of at least 1; n = 0 or an integer of at least 1; X is a polar group selected from -CO2RS, where Rs = H, Na, K, -NHRI, -NRIRII or RIII; -CH3OH; -CH3NH2; -CH3NHR1; or -CH3NRIRII; wherein RI, RII and RIII are independently selected from C1-C6 alkyl or an aryl group, preferably a hydrophilically substituted C1-C6 alkyl or aryl group, or RIII is an esterif?ed glycol; and wherein 20 > m + n + p + 2q = 2; is useful for the treatment of ringworm infection caused by Trichophyton tonsurans.</p> |