摘要 |
<p>The diagnosis of an enteropathic disease or the response of a patient with an enteropathic disease to therapy, in a clinical trial setting or in a long-term disease management setting, is assessed by detecting the ability of the patient to metabolize an orally administered gluten peptide analog. The peptide metabolism may be monitored in a variety of ways. Conveniently, the appearance of a metabolite of the peptide is detected in a patient sample over a period of time following oral administration, e.g. in urine, plasma, breath, saliva, etc. The gluten peptide analog is optionally labeled, e.g. with an isotopic, fluorescent, etc. label.</p> |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;BETHUNE, MICHAEL, THOMAS;KHOSLA, CHAITAN |
发明人 |
BETHUNE, MICHAEL, THOMAS;KHOSLA, CHAITAN |