发明名称 |
1-Ä2H-1-BENZOPYRAN-2-ONE-8-YLÜ- PIPERAZINDERIVATIVE ZUR BEHANDLUNG VON BEWEGUNGSSTÖRUNGEN |
摘要 |
The invention relates to a novel use of known 1-[2H-1-benzopyran-2-one-8-yl]-piperazine derivatives, broad spectrum 5-HT receptor binding compounds, having amongst other functional serotonin receptor activities, potent 5-HT<SUB>1A </SUB>receptor agonistic activity, 5-Ht<SUB>1D </SUB>receptor antagonistic activity and 5-HT<SUB>7 </SUB>receptor agonistic activity. The compounds of the invention are useful for the preparation of medicaments for treating, ameliorating or preventing movement disorders. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description. |
申请公布号 |
AT446757(T) |
申请公布日期 |
2009.11.15 |
申请号 |
AT20050717127T |
申请日期 |
2005.03.23 |
申请人 |
SOLVAY PHARMACEUTICALS B.V. |
发明人 |
BAKKER, CORNELIS;GLENNON, JEFFREY C.;HESSELINK, MAYKE B.;THAETE, CLAUDIA;MCCREARY, ANDREW;VAN SCHARRENBURG, GUSTAAF J. |
分类号 |
A61K31/496;A61K31/00;A61P25/14;A61P25/16 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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