发明名称 |
PEPTIDE HOMING TO BRAIN TUMORS |
摘要 |
The present invention relates to a peptide, which specifically homes to the intracranial, early stage astrocytoma model that grows as islets and harbors co-opted tumor vessels in the brain. The peptide finds its use in targeted delivery of therapeutic substances to invasive brain cancer or metastatic brain lesions as such and in combination with conventional therapies, such as surgery and radiation, and anti-angiogenic therapies, and as a tool in diagnosis of, e.g., invasive brain cancer or metastatic brain lesions.
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申请公布号 |
CA2723887(A1) |
申请公布日期 |
2009.11.12 |
申请号 |
CA20092723887 |
申请日期 |
2009.05.08 |
申请人 |
LAAKKONEN, PIRJO;BURNHAM INSTITUTE FOR MEDICAL RESEARCH;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF CALIFORINA SA N FRANCISCO ("UCSF") |
发明人 |
LAAKKONEN, PIRJO;RUOSLAHTI, ERKKI;BERGERS, GABRIELE |
分类号 |
C07K7/06;A61K38/08;A61P35/00 |
主分类号 |
C07K7/06 |
代理机构 |
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地址 |
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