发明名称 METHODS OF TREATMENT USING AMMONIA-SCAVENGING DRUGS
摘要 <p>The invention provides a method for determining a dose and schedule and making dose adjustments of PBA prodrugs used to treat nitrogen retention states, or ammonia accumulation disorders, by measuring urinary excretion of phenylacetylglutamine and/or total urinary nitrogen. The invention provides methods to select an appropriate dosage of a PBA prodrug based on the patient's dietary protein intake, or based on previous treatments administered to the patient. The methods are applicable to selecting or modifying a dosing regimen for a subject receiving an orally administered ammonia scavenging drug.</p>
申请公布号 WO2009134460(A1) 申请公布日期 2009.11.05
申请号 WO2009US30362 申请日期 2009.01.07
申请人 HYPERION THERAPEUTICS;SCHARSCHMIDT, BRUCE 发明人 SCHARSCHMIDT, BRUCE
分类号 A01N37/10;A61K31/19 主分类号 A01N37/10
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