| 发明名称 |
CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS |
| 摘要 |
<p>Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.</p> |
| 申请公布号 |
SI0951466(T1) |
申请公布日期 |
2009.10.31 |
| 申请号 |
SI19970030787T |
申请日期 |
1997.12.22 |
| 申请人 |
ELAN PHARMACEUTICALS, INC.;ELI LILLY AND COMPANY |
发明人 |
WU JING;TUNG JAY S.;THORSETT EUGENE D.;PLEISS MICHAEL A.;NISSEN JEFFREY S.;NEITZ JEFFREY;LATIMER LEE H.;JOHN VARGHESE;FREEDMAN STEPHEN;BRITTON THOMAS C.;AUDIA JAMES E.;REEL JON K.;MABRY THOMAS E.;DRESSMAN BRUCE A.;CWI CYNTHIA L.;DROSTE JAMES J.;HENRY STEVEN S.;MCDANIEL STACEY L.;SCOTT WILLIAM L.;STUCKY RUSSELL D.;PORTER WARREN J. |
| 分类号 |
C07D243/16;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61K38/00;A61P25/28;A61P43/00;C07C;C07C237/22;C07D207/26;C07D207/273;C07D211/76;C07D223/10;C07D223/16;C07D223/18;C07D243/12;C07D243/24;C07D243/38;C07D267/14;C07D281/10;C07D307/33;C07D309/30;C07D401/04;C07D401/14;C07D409/12;C07D409/14;C07D487/04;C07K5/087;C07K5/113;C07K14/18 |
主分类号 |
C07D243/16 |
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