| 摘要 |
The present invention relates to a group of substituted-7-azabicyclo--[2.2.1]heptyl derivatives with biological activity . The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo--[2 2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2 2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl deriva-tives, as well as their u se as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter--gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.
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