| 发明名称 |
(Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists |
| 摘要 |
The present invention relates to compounds of formula 1: and pharmaceutically acceptable acid addition sails thereof. The compounds of the present invention are useful for activating 5-HT1F receptors, inhibiting neuronal protein extravasation, and for the treatment or preverition of migraine in mammals, particularly humans.
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| 申请公布号 |
US7608629(B2) |
申请公布日期 |
2009.10.27 |
| 申请号 |
US20050552131 |
申请日期 |
2005.10.11 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BLANCO-PILLADO MARIA-JESUS;BENESH DANA RAE;FILLA SANDRA ANN;HUDZIAK KEVIN JOHN;MATHES BRIAN MICHAEL;KOHLMAN DANIEL TIMOTHY;YING BAI-PING;ZHANG DEYI;XU YAO-CHANG |
| 分类号 |
A61K31/4545;A61P25/06;C07D211/44;C07D211/54;C07D401/12;C07D401/14;C07D409/12 |
主分类号 |
A61K31/4545 |
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