发明名称 |
METAP-2 INHIBITOR POL?MERSOMES FOR THERAPEUTIC ADMINISTRATION |
摘要 |
Described herein are MetAP-2 inhibitors and compositions and formulations thereof, and more particularly compositions and formulations of MetAP-2 inhibitors wherein the MetAP-2 inhibitor is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. The present invention also relates to compositions and formulations comprising MetAP-2 inhibitors for oral administration or administration via routes such as topical or ocular administration. The present invention also provides methods to treat conditions associated with or related to the over-expression or over-activity of MetAP-2 by administering the compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. |
申请公布号 |
WO2009003110(A3) |
申请公布日期 |
2009.10.22 |
申请号 |
WO2008US68367 |
申请日期 |
2008.06.26 |
申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;BENNY-RATSABY, OFRA |
发明人 |
BENNY-RATSABY, OFRA |
分类号 |
A61K47/48;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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