发明名称 beta-ketoamide compounds with MCH antagonistic activity
摘要 Compounds of formula I wherein the groups and residues A, B, b, X, Y, Z, R1, R2, R3, R5a and R5b have the meanings given in claim 1. The invention further relates to pharmaceutical compositions containing at least one amide according to the invention. As a result of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia, and diabetes.
申请公布号 US7605176(B2) 申请公布日期 2009.10.20
申请号 US20050071797 申请日期 2005.03.03
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 ROTH GERALD JUERGEN;LUSTENBERGER PHILIPP;STENKAMP DIRK;MUELLER STEPHAN GEORG;LEHMANN-LINTZ THORSTEN;SCHINDLER MARCUS;THOMAS LEO;LOTZ RALF R. H.;SANTAGOSTINO MARCO
分类号 A01N43/36;A61K31/454;A61K31/4709;A61K31/4747;A61K31/496;A61K31/5377;A61K31/541;A61K31/55;C07C235/74;C07D205/04;C07D207/00;C07D207/08;C07D207/20;C07D209/08;C07D211/42;C07D211/46;C07D211/48;C07D211/52;C07D211/58;C07D211/62;C07D221/20;C07D263/56;C07D295/00;C07D295/092;C07D295/135;C07D401/12;C07D413/02;C07D417/02 主分类号 A01N43/36
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