发明名称 Polymorphic forms of (S)-1-tetrahydrofuran-3-yl-3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzyl carbamate
摘要 The present invention relates to polymorphic forms of (S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate (Compound 1): and pharmaceutical compositions thereof. The present invention also relates to processes to prepare compound 1 and pharmaceutical compositions thereof. Compound 1 is an IMPDH inhibitor useful in treating IMPDH-mediated diseases such as immune system related diseases, viral diseases, and cancers.
申请公布号 US7605270(B2) 申请公布日期 2009.10.20
申请号 US20060429811 申请日期 2006.05.08
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 BLYTHE TODD;EBERLIN ALEX;HURREY MICHAEL;JONAITIS DAVID;NYCE PHILIP;PARENT STEPHAN;SNOONIAN JOHN
分类号 C07D263/32 主分类号 C07D263/32
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