发明名称 |
Polymorphic forms of (S)-1-tetrahydrofuran-3-yl-3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzyl carbamate |
摘要 |
The present invention relates to polymorphic forms of (S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate (Compound 1): and pharmaceutical compositions thereof. The present invention also relates to processes to prepare compound 1 and pharmaceutical compositions thereof. Compound 1 is an IMPDH inhibitor useful in treating IMPDH-mediated diseases such as immune system related diseases, viral diseases, and cancers.
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申请公布号 |
US7605270(B2) |
申请公布日期 |
2009.10.20 |
申请号 |
US20060429811 |
申请日期 |
2006.05.08 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
BLYTHE TODD;EBERLIN ALEX;HURREY MICHAEL;JONAITIS DAVID;NYCE PHILIP;PARENT STEPHAN;SNOONIAN JOHN |
分类号 |
C07D263/32 |
主分类号 |
C07D263/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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