| 发明名称 |
Compositions and processes using siRNA, amphipathic compounds and polycations |
| 摘要 |
Described is a deliverable composition with low toxicity comprising an amphipathic compound, a polycation, and a siRNA. The composition may be used in the process of delivering a siRNA to an animal cell or more particularly, a mammal cell.
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| 申请公布号 |
US7601367(B2) |
申请公布日期 |
2009.10.13 |
| 申请号 |
US20040845968 |
申请日期 |
2004.05.14 |
| 申请人 |
MIRUS BIO LLC |
发明人 |
MONAHAN SEAN D.;LEWIS DAVID L.;HERWEIJER HANS;WOLFF JON A.;HAGSTROM JAMES E.;LOOMIS AARON G.;TRUBETSKOY VLADIMIR;HIGGS LORI |
| 分类号 |
A61K9/127;A61K31/495;A61K31/58;A61K31/7105;A61K31/74;A61K48/00;C07H21/04;C12N15/11;C12N15/88 |
主分类号 |
A61K9/127 |
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