发明名称 Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor
摘要 The present invention is a new stable drug composition particularly suitable for use as an antihypercholesterolaemic or antihyperlipidaemic agent. The present invention is specifically a drug composition comprising a pharmaceutical, a complexing agent and a surfactant, and a method for manufacturing same. When applied to unstable drugs with low solubility and poor bioavailability, like HMG-CoA reductase inhibitors and especially atorvastatin calcium amorphous form, the resulting drug composition is more stable and is characterized by an improved dissolution profile.
申请公布号 US2009247603(A1) 申请公布日期 2009.10.01
申请号 US20050315986 申请日期 2005.12.23
申请人 ORBUS PHARMA, INC. 发明人 JOSHI LAXMINARAYAN
分类号 A61K31/40 主分类号 A61K31/40
代理机构 代理人
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