| 摘要 |
Compounds of formula (I) wherein R1 is H, C1-C3-alkyl, C3-C5-cycloalkyl or C1-C3-perfluoroalkyl, R2 is H, C1-C6-alkyl optionally substituted by OH, C1-C3-alkoxy or C1-C3-perfluoroalkyl, R3 is C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkinyl, C3-C7-cycloalkyl, C1-C6-perfluoroalkyl or C3-C6-cycloalkyl-C1-C6-alkyl, R4=H, ADT-OH, cysteine, agmatine, arginine, aminoguanidine or agents releasing or stimulating the release of hydrogen sulfide, and salts thereof. The compounds are suitable for treating impotence, cardiovascular disorders, diseases characterized by disorders of gut motility, gastropathy of diabetic and nondiabetic origin, in general diseases where cytoprotection is important.
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