发明名称 |
Ethylenedicysteine (EC)-drug conjugates compositions and methods for tissue specific disease imaging |
摘要 |
The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided. |
申请公布号 |
US7582281(B2) |
申请公布日期 |
2009.09.01 |
申请号 |
US20070627299 |
申请日期 |
2007.01.25 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
YANG DAVID J.;LIU CHUN W.;YU DONG-FANG;KIM E. EDMUND |
分类号 |
A61K51/00;A61K51/04;A61K51/08;A61M36/14 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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