发明名称 Ethylenedicysteine (EC)-drug conjugates compositions and methods for tissue specific disease imaging
摘要 The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
申请公布号 US7582281(B2) 申请公布日期 2009.09.01
申请号 US20070627299 申请日期 2007.01.25
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 YANG DAVID J.;LIU CHUN W.;YU DONG-FANG;KIM E. EDMUND
分类号 A61K51/00;A61K51/04;A61K51/08;A61M36/14 主分类号 A61K51/00
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